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It is the leading cause of death worldwide, accounting for 30% of deaths.
Cardiovascular disease (CVD) refers to a group of disorders affecting the heart and blood vessels. It includes conditions such as coronary artery disease (CAD), cerebrovascular disease (including stroke), peripheral artery disease (PAD), and aortic atherosclerosis. CVD is the leading cause of death globally, accounting for approximately 30% of all deaths worldwide.
Key risk factors for CVD include high blood pressure, high LDL cholesterol, smoking, diabetes, obesity, poor diet, physical inactivity, and excessive alcohol use. Prevention and management strategies focus on addressing these risk factors through lifestyle changes, medications, and in some cases, surgical interventions.
The APOE4 allele (a variant of the apolipoprotein E gene) has been associated with an increased risk of cardiovascular diseases (CVD). Studies have shown that individuals carrying the APOE4 allele tend to have higher levels of low-density lipoprotein cholesterol (LDL-C), which is a major risk factor for atherosclerosis and coronary artery disease (CAD).
Diagnosing Cardiovascular Disease (CVD) involves a combination of medical history, physical exams, and various tests. Here are some common diagnostic methods:
- Medical History and Physical Exam: Your doctor will ask about your symptoms, medical history, and family history of heart disease. They will also perform a physical exam, including checking your blood pressure and listening to your heart and lungs.
- Blood Tests: These tests can check for levels of certain substances in your blood, such as cholesterol, triglycerides, and blood sugar, which can indicate heart disease risk.
- Electrocardiogram (ECG or EKG): This test records the electrical activity of your heart and can help detect irregular heartbeats, heart damage, and other heart conditions.
- Echocardiogram: This test uses sound waves to create images of your heart, showing how well your heart is pumping and whether there are any structural abnormalities.
- Stress Test: This test involves exercising on a treadmill or stationary bike while your heart is monitored. It helps determine how well your heart handles physical activity.
- Cardiac Catheterization and Angiogram: In this procedure, a thin tube (catheter) is inserted into a blood vessel and guided to your heart. Dye is injected to make the arteries visible on X-ray, helping to identify blockages.
- CT Scan and MRI: These imaging tests provide detailed pictures of your heart and blood vessels, helping to detect any abnormalities.
Preventing Cardiovascular Disease (CVD) involves making lifestyle changes and managing risk factors to promote heart health. Here are some key prevention strategies:
- Healthy Diet: Eat a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats. Limit salt, saturated fats, trans fats, and added sugars, and opt for heart-healthy foods like nuts, seeds, and fatty fish rich in omega-3 fatty acids.
- Regular Exercise: Engage in at least 150 minutes of moderate aerobic activity or 75 minutes of vigorous activity each week.
- Maintain a Healthy Weight: Achieve and maintain a healthy body weight through a balanced diet and regular physical activity.
- Avoid Tobacco: Quit smoking and avoid exposure to secondhand smoke.
- Limit Alcohol: Drink alcohol in moderation, if at all. This means up to one drink per day for women and up to two drinks per day for men.
- Manage Stress: Engage in activities that promote relaxation and well-being.
- Regular Health Check-ups: Monitor blood pressure, cholesterol levels, and blood sugar levels regularly.
- Medications: If prescribed, take medications for high blood pressure, high cholesterol, or diabetes as directed by your healthcare provider.
To adapt these lifestyle changes and control risk factors more quickly, Biocross provides clinicians with a quick and easy method that allows patients with an increased risk of cardiovascular disease to incorporate these new lifestyle habits even before the onset of the first symptoms, helping to improve their overall heart health.