Diagnosis of Alzheimer’s disease
The current challenges
Until recently, the diagnosis of AD was based on clinical and neuropsychological evaluations performed by a neurologist. However, Latest guidelines from Alzheimer´s Association and National Institute of aging (NIA)3, proposed a biological definition of AD based only in biomarkers, where a patient will be placed within the “AD continuum” depending on the results of tests that measure the brain accumulation of AB peptide, Tau and neurodegeneration. Although accurate tests from these biomarkers are available, most of them require invasive or expensive techniques, such as extraction of cerebrospinal fluid by lumbar puncture or neuroimaging. As a consequence, these techniques cannot be prescribed to all patients and are not available in all medical centers, and there is a demand for cost-effective and simple tests that can reflect the alteration of those biomarkers in a non-invasive way.
Among other drawbacks, technical and logistical issues hamper the widespread application of these biomarkers in general clinical practice:
- They are expensive
- It’s required trained personnel to interpret the results
- They are not yet fully standardized
- In some cases involve invasive procedures
The development of biomarkers that could be measured directly in blood would greatly facilitate the implementation and use of biomarkers for clinical diagnosis.
Diagnosis of Alzheimer’s disease
To fulfill this unmet need, Biocross has developed a series of blood-based diagnostic kits for the identification of AD patients throughout all stages of the disease spectrum, i.e., from the detection of at-risk individuals to the diagnosis of AD, even at the earliest stages.
To fulfill this unmet need, Biocross has developed a series of blood-based diagnostic kits for the identification of AD patients throughout all stages of the disease spectrum, i.e., from the detection of at-risk individuals to the diagnosis of AD, even at the earliest stages.
Biocross’ kits are simple, provide rapid results, and are designed for easy incorporation into
the clinical routine of hospitals.
the clinical routine of hospitals.
Biocross’ kits are simple, provide rapid results, and are designed for easy incorporation into
the clinical routine of hospitals.
the clinical routine of hospitals.
If you have any questions or comments, we will be pleased to attend you
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